Below is my borders scheme. However with veggies and annuals the planting scheme continues to vary.
As you said you have big space. You can divide it into small borders/plots of your choice of size/design. Consideration should be that each border part should be assessable for watering, weeding, hoeing, harvesting etc.
You can space your border/design them as you like. However do separate them with let say 1 foot spacing. Use each bed preferably for one or two veggies.
No major concerns with companion planting that i for see.
Further if you have any query.